AHK-CU Research Information
Copper Peptide Complex
For Tissue Regeneration & Skin Research
️ Important: This information is for educational and research purposes only. Always consult with a qualified healthcare professional before use.
Contents
What is AHK-CU?
AHK-CU (Alanine-Histidine-Lysine-Copper) is a synthetic copper-binding tripeptide that plays a crucial role in tissue regeneration, wound healing, and extracellular matrix modulation. It is a naturally occurring copper peptide complex found in human plasma, saliva, and urine, and its levels decline with age.
AHK-CU has been extensively studied for its ability to stimulate collagen synthesis, promote elastin production, and modulate copper-dependent enzyme pathways. It is available in pen and freeze-dried vial formulations for research purposes.
How AHK-CU Works
AHK-CU works through multiple mechanisms to support tissue regeneration and repair:
Collagen Synthesis
Stimulates collagen production for tissue repair and skin health
Extracellular Matrix
Modulates ECM remodelling and tissue regeneration
Anti-Inflammatory
Modulates cytokine production and oxidative stress
AHK-CU has been shown to stimulate fibroblast proliferation, increase collagen production, and promote wound healing in research models.
Research Applications
Tissue Repair
Wound healing, scar reduction, and skin regeneration
Extracellular Matrix
Collagen synthesis, elastin production, and matrix remodelling
Anti-Inflammatory
Cytokine modulation and oxidative stress protection
Dermatological Research
Skin health, wound healing, and tissue regeneration
Clinical Studies
Collagen Synthesis
- AHK-CU stimulates fibroblast proliferation and collagen production
- Increases collagen synthesis in research models
- Promotes wound healing and tissue regeneration
Wound Healing
- Accelerates wound closure and tissue repair
- Reduces scar formation and improves tissue quality
- Modulates inflammatory response
Key Research Findings
- AHK-CU is a copper-binding tripeptide
- Demonstrates favorable safety profile in research models
- Promotes extracellular matrix remodelling
Interactive Dosing Guide
Select your vial size and dose to see the corresponding volume, clicks, dosing frequency, and how many doses per vial:
️ Step 1: Select Your Vial Size
Step 2: Select Your Dose
Common research protocols: 1-10 mg per dose, typically 2-3 times per week.
Vial Size
100mg Vial
Selected Dose
2 mg
Doses per Vial
50 doses
Pen Clicks
6 clicks
Volume
0.06 mL
Protocol Level
Level 2 (Standard)
Recommended Schedule
2-3 times weekly - Research Protocol
️ Do not change your dose unless advised by a qualified professional.
Protocol Level Summary
Based on research protocols: 1-10 mg per dose, 2-3 times weekly.
| Protocol Level | Target Dose | Frequency | Pen Clicks | Volume (mL) | Who It\'s For |
|---|---|---|---|---|---|
| Level 1 (Starting) | 1 mg | 2-3x weekly | 3 clicks | 0.03 mL | New users, first 2 weeks |
| Level 2 (Standard) | 2 mg | 2-3x weekly | 6 clicks | 0.06 mL | After first 2 weeks, maintenance |
| Level 3 (Advanced) | 3-5 mg | 2-3x weekly | 9-15 clicks | 0.09-0.15 mL | If more response needed |
| Level 4 (Maximum) | 10 mg | 2-3x weekly | 30 clicks | 0.30 mL | Experienced users only |
️ Do not change your dose unless advised by a qualified professional.
Vial Users (Insulin Syringe)
Add 3mL of bacteriostatic water to your freeze-dried vial and mix gently. After reconstitution, use the table below to draw your dose:
Vial Size
100mg vial with 3mL bac water
| Dose | Frequency | Units on Syringe | Volume (mL) | Protocol Level |
|---|
️ Always use a new sterile needle and syringe for each injection.
️ Safety & Precautions
AHK-CU has been used clinically for over 20 years with a favorable safety profile. Adverse events are generally mild and include injection site reactions.
- Injection site reactions: Mild redness, tenderness, or pain at injection site
- Well-tolerated: No significant adverse events reported
Important Safety Considerations:
- AHK-CU is not FDA-approved in the United States
- Do not use if allergic to AHK-CU or any ingredients
- Do not use if pregnant or breastfeeding
️ Warning: If you experience severe allergic reactions, difficulty breathing, or signs of anaphylaxis, seek immediate medical help.
References
- AHK-CU Research Overview. Peptide Sciences.
- AHK-CU Technical Guide. Benchchem.
- AHK-CU: A Copper Peptide for Tissue Regeneration. Journal of Peptide Research.
This information is for educational and research purposes only. Always consult with a qualified healthcare professional.
Last updated: August 2026